Wine quickstart guide
This Quickstart Guide will help you to get Wine running. Make sure you have Wine installed. If you don't check this page on installing Wine: http://winehq.org/site/docs/wineusr-guide/getting-wine
Installing an application
The easiest way to install an application is to use winecfg. Just type winecfg on the command line and click on "Add application" and the application will be installed.
After installing there will be a menu entry for the application in the wine menu.
It is also possible to install applications from the command line. Here's how to do it:
In this guide I will show you how to install MS Office.
In order to install an application you must know the name of the file to run and the location of the file.
In this example I must run setup.exe which is loacted in /media/cdrom.
To install Office I must run the following command:
$ wine /media/cdrom/setup.exe
The application will now be installed. 
Running an application
The application will be installed in a directory called .wine in your HOME directory. If your file manager doesn't show this directory make sure that it shows hidden files/directories (.wine is a hidden directory).Office is installed in ~/.wine/drive_c/Program Files/Microsoft Office/Office
If I want to run Word I must type the following lines:
$ cd ~/.wine/drive_c/Program Files/Microsoft\ Office/Office
$ wine winword.exe
It might be a good idea to create a file that launches Word. It could look like this:
#/bin/sh
cd ~/.wine/drive_c/Program Files/Microsoft\ Office/Office
wine winword.exe
Save this as word.sh in ~/bin and make it executable by typing chmod +x word.sh
You can now start Word by typing word.sh